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Mice expressing markedly reduced striatal dopamine transporters exhibit increased locomotor activity, dopamine uptake turnover rate and cocaine responsiveness

Variations in the expression levels of the dopamine transporter (DAT) can influence responsiveness to psychostimulant drugs like cocaine. To better understand this relationship, we studied a new DAT-low expresser (DAT-LE) mouse model and performed behavioral and biochemical studies with it. Immunobl...

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Detalhes bibliográficos
Main Authors: Rao, Anjali, Sorkin, Alexander, Zahniser, Nancy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760678/
https://ncbi.nlm.nih.gov/pubmed/23564231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21671
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