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Human-Mouse Hybrid Cell Lines and Susceptibility to Poliovirus : I. Conversion from Polio Sensitivity to Polio Resistance Accompanying Loss of Human Gene-Dependent Polio Receptors

A number of human-mouse somatic hybrid cell lines have been prepared, containing from 3 to 12 human biarmed chromosomes. These lines were susceptible to poliovirus type 1, producing viral yields comparable to those of the human parental cells. A small proportion of the cells of these lines survived...

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Autores principales: Wang, Richard, Pollack, Robert, Kusano, Toshihisa, Green, Howard
Formato: Artigo
Lenguaje:Inglês
Publicado: 1970
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC376059/
https://ncbi.nlm.nih.gov/pubmed/4317112
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