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Efficient Sampling of Protein Conformational Space Using Fast Loop Building and Batch Minimization on Highly Parallel Computers

All-atom sampling is a critical and compute-intensive end stage to protein structural modeling. Because of the vast size and extreme ruggedness of conformational space, even close to the native structure, the high-resolution sampling problem is almost as difficult as predicting the rough fold of a p...

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Hlavní autoři: Tyka, Michael D., Jung, Kenneth, Baker, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760475/
https://ncbi.nlm.nih.gov/pubmed/22847521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.23069
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