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The role of HSP70 on ENPP1 expression and insulin-receptor activation

Ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) inhibits insulin-receptor (IR) signaling and, when over-expressed, induces insulin resistance in vitro and in vivo. Understanding the regulation of ENPP1 expression may, thus, unravel new molecular mechanisms of insulin resistance. Recent da...

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Main Authors: Marucci, Antonella, Miscio, Giuseppe, Padovano, Libera, Boonyasrisawat, Watip, Florez, Jose C., Doria, Alessandro, Trischitta, Vincenzo, Paola, Rosa Di
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760425/
https://ncbi.nlm.nih.gov/pubmed/19083193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-008-0429-9
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