ENPP1 Affects Insulin Action and Secretion: Evidences from In Vitro Studies

The aim of this study was to deeper investigate the mechanisms through which ENPP1, a negative modulator of insulin receptor (IR) activation, plays a role on insulin signaling, insulin secretion and eventually glucose metabolism. ENPP1 cDNA (carrying either K121 or Q121 variant) was transfected in H...

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Autors principals: Di Paola, Rosa, Caporarello, Nunzia, Marucci, Antonella, Dimatteo, Claudia, Iadicicco, Claudia, Del Guerra, Silvia, Prudente, Sabrina, Sudano, Dora, Miele, Claudia, Parrino, Cristina, Piro, Salvatore, Beguinot, Francesco, Marchetti, Piero, Trischitta, Vincenzo, Frittitta, Lucia
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088669/
https://ncbi.nlm.nih.gov/pubmed/21573217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019462
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