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EM-Fold: De novo Folding of α-helical Proteins Guided by Intermediate Resolution Electron Microscopy Density Maps

Over the last ten years the number of cryoelectron microscopy (cryoEM) experiments yielding medium resolution (7–10 Å) density maps of proteins has greatly increased. At this resolution α-helices can be identified as density rods while β-strand or loop regions are not as easily discerned. Thus, for...

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Hlavní autoři: Lindert, Steffen, Staritzbichler, René, Wötzel, Nils, Karakaş, Mert, Stewart, Phoebe L., Meiler, Jens
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760413/
https://ncbi.nlm.nih.gov/pubmed/19604479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.06.001
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