Variation in the Lysyl Oxidase (LOX) Gene Is Associated with Keratoconus in Family-Based and Case-Control Studies

PURPOSE. Keratoconus is a bilateral noninflammatory progressive corneal disorder with complex genetic inheritance and a common cause for cornea transplantation in young adults. A genomewide linkage scan in keratoconus families identified a locus at 5q23.2, overlapping the gene coding for the lysyl o...

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Main Authors: Bykhovskaya, Yelena, Li, Xiaohui, Epifantseva, Irina, Haritunians, Talin, Siscovick, David, Aldave, Anthony, Szczotka-Flynn, Loretta, Iyengar, Sudha K., Taylor, Kent D., Rotter, Jerome I., Rabinowitz, Yaron S
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760233/
https://ncbi.nlm.nih.gov/pubmed/22661479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-9268
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