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Selected TLR agonist combinations synergistically trigger a T(H)1 polarizing program in dendritic cells
Toll like receptors (TLRs) sense microbial products and initiate adaptive immune responses by activating dendritic cells (DCs). Since pathogens may contain several TLR agonists we asked whether different TLRs synergize in DC activation. In human and mouse DCs TLR3 or TLR4 potently synergized with TL...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760217/ https://ncbi.nlm.nih.gov/pubmed/15995707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1223 |
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