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Effects of age on circadian rhythms are similar in wild-type and heterozygous Clock mutant mice

The amplitudes of many circadian rhythms, at the behavioral, physiological, cellular, and biochemical levels, decrease with advanced age. Previous studies suggest that the amplitude of the central circadian pacemaker is decreased in old animals. Recently, it has been reported that expression of seve...

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Detalhes bibliográficos
Main Authors: Kolker, Daniel E., Vitaterna, Martha Hotz, Fruechte, Ethan M., Takahashi, Joseph S., Turek, Fred W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760160/
https://ncbi.nlm.nih.gov/pubmed/15013573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2003.06.007
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