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ACE Inhibition with Captopril Retards the Development of Signs of Neurodegeneration in an Animal Model of Alzheimer’s Disease

Increased generation of reactive oxygen species (ROS) is a significant pathological feature in the brains of patients with Alzheimer’s disease (AD). Experimental evidence indicates that inhibition of brain ROS could be beneficial in slowing the neurodegenerative process triggered by amyloid-beta (Ab...

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Detalhes bibliográficos
Main Authors: AbdAlla, Said, Langer, Andreas, Fu, Xuebin, Quitterer, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759943/
https://ncbi.nlm.nih.gov/pubmed/23959119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140816917
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