Mild Oxidative Damage in the Diabetic Rat Heart Is Attenuated by Glyoxalase-1 Overexpression

Diabetes significantly increases the risk of heart failure. The increase in advanced glycation endproducts (AGEs) and oxidative stress have been associated with diabetic cardiomyopathy. We recently demonstrated that there is a direct link between AGEs and oxidative stress. Therefore, the aim of the...

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Hauptverfasser: Brouwers, Olaf, de Vos-Houben, Joyce M. J., Niessen, Petra M. G., Miyata, Toshio, van Nieuwenhoven, Frans, Janssen, Ben J. A., Hageman, Geja, Stehouwer, Coen D. A., Schalkwijk, Casper G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International (MDPI) 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759882/
https://ncbi.nlm.nih.gov/pubmed/23899787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140815724
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