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Impaired Pre-mRNA Processing and Altered Architecture of 3′ Untranslated Regions Contribute to the Development of Human Disorders

The biological fate of each mRNA and consequently, the protein to be synthesised, is highly dependent on the nature of the 3′ untranslated region. Despite its non-coding character, the 3′ UTR may affect the final mRNA stability, the localisation, the export from the nucleus and the translation effic...

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Autori principali: Michalova, Eva, Vojtesek, Borivoj, Hrstka, Roman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Diversity Preservation International (MDPI) 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759880/
https://ncbi.nlm.nih.gov/pubmed/23896598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140815681
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