A Practical Approach to Immunotherapy of Hepatocellular Carcinoma Using T Cells Redirected Against Hepatitis B Virus

Hepatocellular carcinoma (HCC) cells often have hepatitis B virus (HBV)-DNA integration and can be targeted by HBV-specific T cells. The use of viral vectors to introduce exogenous HBV-specific T-cell receptors (TCR) on T cells to redirect their specificity is complex and expensive to implement in c...

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Detalhes bibliográficos
Main Authors: Koh, Sarene, Shimasaki, Noriko, Suwanarusk, Rossarin, Ho, Zi Zong, Chia, Adeline, Banu, Nasirah, Wu Howland, Shanshan, Ong, Alice Soh Meoy, Gehring, Adam J, Stauss, Hans, Renia, Laurent, Sällberg, Matti, Campana, Dario, Bertoletti, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Methods - Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759740/
https://ncbi.nlm.nih.gov/pubmed/23941866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.43
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