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Neutralization of HIV-1 by redirection of natural antibodies

The great variability and high glycosylation of gp120 poses a great challenge for the design of a functional immune therapy. The binding region of the CD4 receptor to gp120, however, is well conserved and may constitute a target to limit viral entry and infectivity. Our strategy consists in using a...

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Detalhes bibliográficos
Main Authors: Perdomo, Maria F., Levi, Michael, Sällberg, Matti, Vahlne, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518824/
https://ncbi.nlm.nih.gov/pubmed/18719129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805777105
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