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A new role for the cellular PABP repressor Paip2 as an innate restriction factor capable of limiting productive cytomegalovirus replication

The capacity of polyadenylate-binding protein PABPC1 (PABP1) to stimulate translation is regulated by its repressor, Paip2. Paradoxically, while PABP accumulation promotes human cytomegalovirus (HCMV) protein synthesis, we show that this is accompanied by an analogous increase in the abundance of Pa...

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Detalhes bibliográficos
Main Authors: McKinney, Caleb, Yu, Dong, Mohr, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759697/
https://ncbi.nlm.nih.gov/pubmed/23964095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.221341.113
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