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Cisplatin causes cell death via TAB1 regulation of p53/MDM2/MDMX circuitry

The interdependence of p53 and MDM2 is critical for proper cell survival and cell death and, when altered, can lead to tumorigenesis. Mitogen-activated protein kinase (MAPK) signaling pathways function in a wide variety of cellular processes, including cell growth, migration, differentiation, and de...

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Hlavní autoři: Zhu, Yan, Regunath, Kausik, Jacq, Xavier, Prives, Carol
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759692/
https://ncbi.nlm.nih.gov/pubmed/23934659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.212258.112
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