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Cisplatin causes cell death via TAB1 regulation of p53/MDM2/MDMX circuitry
The interdependence of p53 and MDM2 is critical for proper cell survival and cell death and, when altered, can lead to tumorigenesis. Mitogen-activated protein kinase (MAPK) signaling pathways function in a wide variety of cellular processes, including cell growth, migration, differentiation, and de...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759692/ https://ncbi.nlm.nih.gov/pubmed/23934659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.212258.112 |
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