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Mathematical analysis of multiscale models for hepatitis C virus dynamics under therapy with direct-acting antiviral agents

Chronic hepatitis C virus (HCV) infection remains a world-wide public health problem. Therapy with interferon and ribavirin leads to viral elimination in less than 50% of treated patients. New treatment options aiming at a higher cure rate are focused on direct-acting antiviral agents (DAAs), which...

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Detalhes bibliográficos
Main Authors: Rong, Libin, Perelson, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759661/
https://ncbi.nlm.nih.gov/pubmed/23684949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbs.2013.04.012
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