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Regulation of TNF-α-Induced Microvascular Endothelial Cell Hyperpermeability by Recombinant Bcl-xL
BACKGROUND: Tumor necrosis factor-α (TNF-α), a cytotoxic cytokine, induces endothelial cell barrier dysfunction and microvascular hyperpermeability leading to tissue edema, a hall mark of traumatic injuries. The objective of this study was to determine if Bcl-xL, an anti-apoptotic protein, would reg...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759616/ https://ncbi.nlm.nih.gov/pubmed/23731686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.04.079 |
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