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Characterization of Human T Lymphocytes Engineered to Express IL-15 and HSV-TK
INTRODUCTION: Preclinical studies have demonstrated that tumor reactive T cells expressing the IL-15 transgene had enhanced activity. Gene therapy strategies utilizing IL-15 should include a safety mechanism in anticipation of possible adverse effects because IL-15 overexpression has been implicated...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759574/ https://ncbi.nlm.nih.gov/pubmed/23582229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.03.054 |
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