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Autophagy Alleviates Neurodegeneration Caused by Mild Impairment of Oxidative Metabolism

Thiamine deficiency (TD) causes mild impairment of oxidative metabolism and region-selective neuronal loss in the brain, which may be mediated by neuronal oxidative stress, endoplasmic reticulum stress, and neuroinflammation. TD-induced brain damage is used to model neurodegenerative disorders, and...

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Detalhes bibliográficos
Main Authors: Meng, Ya, Yong, Yue, Yang, Guang, Ding, Hanqing, Fan, Zhiqin, Tang, Yifen, Luo, Jia, Ke, Zun-Ji
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759557/
https://ncbi.nlm.nih.gov/pubmed/23586593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12268
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