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Ethanol Promotes Thiamine Deficiency-Induced Neuronal Death: Involvement of Double-Stranded RNA-activated Protein Kinase

BACKGROUND: Heavy alcohol consumption causes cerebellar degeneration, and the underlying mechanism is unclear. Chronic alcoholism is usually associated with thiamine deficiency (TD) which is known to induce selective neurodegeneration in the brain. However, the role of TD in alcohol-induced cerebell...

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Detalhes bibliográficos
Main Authors: Ke, Zun-Ji, Wang, Xin, Fan, Zhiqin, Luo, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093711/
https://ncbi.nlm.nih.gov/pubmed/19382901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2009.00931.x
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