Blocking the P2X7 Receptor Improves Outcomes After Axonal Fusion

BACKGROUND: Activation of the P2X7 Receptor on nerve cells causes the formation of pannexin pores, which allows the influx of calcium across the cell membrane. Polyethylene glycol (PEG) and methylene blue (MB) have previously been shown to delay Wallerian degeneration if applied during microsuture r...

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Hauptverfasser: Rodriguez-Feo, Charles L., Sexton, Kevin W., Boyer, Richard B., Pollins, Alonda C., Cardwell, Nancy L., Nanney, Lillian B., Shack, R. Bruce, Mikesh, Michelle A, McGill, Christopher H, Driscoll, Christopher W, Bittner, George D., Thayer, Wesley P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759537/
https://ncbi.nlm.nih.gov/pubmed/23731685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.04.082
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