Blocking the P2X7 Receptor Improves Outcomes After Axonal Fusion

BACKGROUND: Activation of the P2X7 Receptor on nerve cells causes the formation of pannexin pores, which allows the influx of calcium across the cell membrane. Polyethylene glycol (PEG) and methylene blue (MB) have previously been shown to delay Wallerian degeneration if applied during microsuture r...

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Autori principali: Rodriguez-Feo, Charles L., Sexton, Kevin W., Boyer, Richard B., Pollins, Alonda C., Cardwell, Nancy L., Nanney, Lillian B., Shack, R. Bruce, Mikesh, Michelle A, McGill, Christopher H, Driscoll, Christopher W, Bittner, George D., Thayer, Wesley P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759537/
https://ncbi.nlm.nih.gov/pubmed/23731685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.04.082
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