Regulation of the Pro-inflammatory Cytokine Osteopontin by GIP in Adipocytes - A role for the Transcription Factor NFAT and Phosphodiesterase 3B

The incretin - glucose-dependent insulinotropic polypeptide (GIP) - and the pro-inflammatory cytokine osteopontin are known to have important roles in the regulation of adipose tissue functions. In this work we show that GIP stimulates lipogenesis and osteopontin expression in primary adipocytes. Th...

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Detalhes bibliográficos
Main Authors: Omar, Bilal, Banke, Elin, Guiguis, Emilia, Åkesson, Lina, Manganiello, Vincent, Lyssenko, Valeriya, Groop, Leif, Gomez, Maria F., Degerman, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759516/
https://ncbi.nlm.nih.gov/pubmed/22892131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.07.157
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