Depletion of CD4(+) CD25(+) Regulatory T Cells Promotes CCL21-Mediated Antitumor Immunity

CCL21 is known to attract dendritic cells (DCs) and T cells that may reverse tumor-mediated immune suppression. The massive infiltration of tumors by regulatory T cells (Tregs) prevents the development of a successful helper immune response. In this study, we investigated whether elimination of CD4(...

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Bibliographic Details
Main Authors:	Zhou, Shuang, Tao, Huihong, Zhen, Zhiwei, Chen, Haixia, Chen, Guolin, Yang, Yaoqin
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2013
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3759453/ https://ncbi.nlm.nih.gov/pubmed/24023916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073952
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Depletion of CD4(+) CD25(+) Regulatory T Cells Promotes CCL21-Mediated Antitumor Immunity

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