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Depletion of CD4(+) CD25(+) Regulatory T Cells Promotes CCL21-Mediated Antitumor Immunity
CCL21 is known to attract dendritic cells (DCs) and T cells that may reverse tumor-mediated immune suppression. The massive infiltration of tumors by regulatory T cells (Tregs) prevents the development of a successful helper immune response. In this study, we investigated whether elimination of CD4(...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759453/ https://ncbi.nlm.nih.gov/pubmed/24023916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073952 |
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