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Rapamycin Enhances Adenovirus-Mediated Cancer Imaging and Therapy in Pre-Immunized Murine Hosts

Tumor-specific adenoviral vectors comprise a fruitful gene-based diagnostic imaging and therapy research area for advanced stage of cancer, including metastatic disease. However, clinical translation of viral vectors has encountered considerable obstacles, largely due to host immune responses agains...

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Bibliographic Details
Main Authors: Jiang, Ziyue Karen, Johnson, Mai, Moughon, Diana L., Kuo, Jennifer, Sato, Makoto, Wu, Lily
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759448/
https://ncbi.nlm.nih.gov/pubmed/24023896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073650
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