Pivotal Role of Matrix Metalloproteinase 13 in Extracellular Matrix Turnover in Idiopathic Pulmonary Fibrosis

RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by excessive deposition of extracellular matrix (ECM). OBJECTIVES: We investigated the regulation of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lung fibrosis. METHODS: MMP and TIMP expression, colla...

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Hauptverfasser: Nkyimbeng, Takwi, Ruppert, Clemens, Shiomi, Takayuki, Dahal, Bhola, Lang, György, Seeger, Werner, Okada, Yasunori, D’Armiento, Jeanine, Günther, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759404/
https://ncbi.nlm.nih.gov/pubmed/24023851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073279
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