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Transgenic expression of human matrix metalloproteinase-1 attenuates pulmonary arterial hypertension in mice

PAH (pulmonary arterial hypertension) is a debilitating and life-threatening disease, often affecting young people. We specifically expressed human MMP-1 (matrix metalloproteinase-1) in mouse macrophages and examined its effects in attenuating the decompensating features of MCT (monocrotaline)-induc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: GEORGE, Joseph, SUN, Jie, D’ARMIENTO, Jeanine
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745775/
https://ncbi.nlm.nih.gov/pubmed/21793800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20110295
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