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Arsenite Suppression of BMP Signaling in Human Keratinocytes

Arsenic, a human skin carcinogen, suppresses differentiation of cultured keratinocytes. Exploring the mechanism of this suppression revealed that BMP-6 greatly increased levels of mRNA for keratins 1 and 10, two of the earliest differentiation markers expressed, a process prevented by co-treatment w...

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Detalhes bibliográficos
Main Authors: Phillips, Marjorie A., Qin, Qin, Hu, Qin, Zhao, Bin, Rice, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759367/
https://ncbi.nlm.nih.gov/pubmed/23566955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.02.017
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