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Functional roles of K(ATP) channel subunits in metabolic inhibition

ATP-sensitive potassium channel (K(ATP)) activation can drastically shorten action potential duration (APD) in metabolically compromised myocytes. We showed previously that SUR1 with Kir6.2 forms the functional channel in mouse atria while Kir6.2 and SUR2A predominate in ventricles. SUR1 is more sen...

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Autori principali: Glukhov, Alexey V., Uchida, Keita, Efimov, Igor R., Nichols, Colin G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759354/
https://ncbi.nlm.nih.gov/pubmed/23624089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.04.016
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