Sulfonylurea and K(+)-Channel Opener Sensitivity of K(ATP) Channels: Functional Coupling of Kir6.2 and Sur1 Subunits

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• Compound heterozygous mutations in the SUR1 (ABCC 8) subunit of pancreatic K(ATP) channels cause neonatal diabetes by perturbing the coupling between Kir6.2 and SUR1 subunits
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