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The Shape of the Lymphocyte Receptor Repertoire: Lessons from the B Cell Receptor

Both the B cell receptor (BCR) and the T cell receptor (TCR) repertoires are generated through essentially identical processes of V(D)J recombination, exonuclease trimming of germline genes, and the random addition of non-template encoded nucleotides. The naïve TCR repertoire is constrained by thymi...

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Hlavní autoři: Jackson, Katherine J. L., Kidd, Marie J., Wang, Yan, Collins, Andrew M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759170/
https://ncbi.nlm.nih.gov/pubmed/24032032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00263
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