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The Shape of the Lymphocyte Receptor Repertoire: Lessons from the B Cell Receptor
Both the B cell receptor (BCR) and the T cell receptor (TCR) repertoires are generated through essentially identical processes of V(D)J recombination, exonuclease trimming of germline genes, and the random addition of non-template encoded nucleotides. The naïve TCR repertoire is constrained by thymi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759170/ https://ncbi.nlm.nih.gov/pubmed/24032032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00263 |
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