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E2F1 effects on osteoblast differentiation and mineralization are mediated through up-regulation of frizzled-1
Frizzled homolog 1 (FZD1) is a transmembrane receptor that mediates Wnt signaling. The transcriptional regulation of FZD1 and the role of FZD1 in osteoblast biology are not well understood. We examined the role of E2F1 in FZD1 promoter activation and osteoblast differentiation and mineralization. A...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758927/ https://ncbi.nlm.nih.gov/pubmed/23806799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.06.019 |
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