Phase II Study of Satraplatin and Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer: A Pharmacogenetic Assessment of Outcome and Toxicity

Genetic polymorphisms in DNA repair enzymes (excision repair cross-complementing group 1 [ERCC1] and x-ray cross-complementing group 1 [XRCC1]) may predict treatment outcome and response to platinum-based treatment. Twenty-four patients were enrolled in this single-arm study to assess the associatio...

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Bibliografiske detaljer
Main Authors: Figg, William D., Chau, Cindy H., Madan, Ravi A., Gulley, James L., Gao, Rui, Sissung, Tristan M., Spencer, Shawn, Beatson, Melony, Aragon-Ching, Jeanny, Steinberg, Seth M., Dahut, William L.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758779/
https://ncbi.nlm.nih.gov/pubmed/23684781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clgc.2013.04.007
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