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Prostaglandin E2 affects T cell responses through modulation of CD46 expression()

The ubiquitous protein CD46, a regulator of complement activity, promotes T cell activation and differentiation towards a regulatory Tr1-like phenotype. CD46-mediated differentiation pathway is defective in several chronic inflammatory diseases, underlying the importance of CD46 in controlling T cel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kickler, Karoline, Maltby, Kathryn, Choileain, Siobhan Ni, Stephen, Jillian, Wright, Sheila, Hafler, David A., Jabbour, Henry N., Astier, Anne L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758685/
https://ncbi.nlm.nih.gov/pubmed/22544928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103090
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