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A circadian sleep disorder reveals complexity in the clock

Circadian rhythms are established by transcription of clock genes and autoregulatory transcriptional feedback loops. In this issue, Xu et al. (2007), characterize mice expressing a human Per2 mutation identified in patients with Familial Advanced Sleep Phase Syndrome. Their results reveal that PER2...

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Detalhes bibliográficos
Main Authors: Mignot, Emmanuel, Takahashi, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758472/
https://ncbi.nlm.nih.gov/pubmed/17218251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.12.024
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