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Bone Collagen: New Clues to its Mineralization Mechanism From Recessive Osteogenesis Imperfecta

Until 2006 the only mutations known to cause osteogenesis imperfecta (OI) were in the two genes coding for type I collagen chains. These dominant mutations affecting the expression or primary sequence of collagen α1(I) and α2(I) chains account for over 90% of OI cases. Since then a growing list of m...

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Detalhes bibliográficos
Main Authors: Eyre, David R., Ann Weis, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758449/
https://ncbi.nlm.nih.gov/pubmed/23508630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-013-9723-9
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