Differential Inhibition of Ex-Vivo Tumor Kinase Activity by Vemurafenib in BRAF(V600E) and BRAF Wild-Type Metastatic Malignant Melanoma

BACKGROUND: Treatment of metastatic malignant melanoma patients harboring BRAF(V600E) has improved drastically after the discovery of the BRAF inhibitor, vemurafenib. However, drug resistance is a recurring problem, and prognoses are still very bad for patients harboring BRAF wild-type. Better marke...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tahiri, Andliena, Røe, Kathrine, Ree, Anne H., de Wijn, Rik, Risberg, Karianne, Busch, Christian, Lønning, Per E., Kristensen, Vessela, Geisler, Jürgen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2013
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758344/
https://ncbi.nlm.nih.gov/pubmed/24023633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072692
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