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Expression, purification, crystallization and preliminary X-ray crystallographic analysis of human myosin 1c in complex with calmodulin
Myosin 1c (Myo1c) is implicated in several cellular processes such as vesicle transport and the mediation of adaptation in the inner ear. Consequently, mutations impairing Myo1c motor activity lead to hearing loss in humans. To understand the role of Myo1c in this process on a molecular level, its c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758153/ https://ncbi.nlm.nih.gov/pubmed/23989153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113020988 |
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