Arsenite stabilizes HIF-1α protein through p85α-mediated up-regulation of inducible Hsp70 protein expression

Hypoxia-inducible factor-1α (HIF-1α) has been reported to regulate over 100 gene expressions in response to hypoxia and other stress conditions. In the present study, we found that arsenite could induce HIF-1α protein accumulation in both mouse epidermal Cl41 cells and mouse embryonic fibroblasts (M...

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Detalhes bibliográficos
Main Authors: Guo, Wei, Yang, Zhuo, Xia, Qing, Liu, Jinyi, Yu, Yonghui, Li, Jingxia, Zuo, Zhenghong, Zhang, Dongyun, Li, Xueyong, Shi, Xianglin, Huang, Chuanshu
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758129/
https://ncbi.nlm.nih.gov/pubmed/20835880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0459-7
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