The Luminal Progenitor Compartment of the Normal Human Mammary Gland Constitutes a Unique Site of Telomere Dysfunction

Telomeres are essential for genomic integrity, but little is known about their regulation in the normal human mammary gland. We now demonstrate that a phenotypically defined cell population enriched in luminal progenitors (LPs) is characterized by unusually short telomeres independently of donor age...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kannan, Nagarajan, Huda, Nazmul, Tu, LiRen, Droumeva, Radina, Aubert, Geraldine, Chavez, Elizabeth, Brinkman, Ryan R., Lansdorp, Peter, Emerman, Joanne, Abe, Satoshi, Eaves, Connie, Gilley, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2013
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757746/
https://ncbi.nlm.nih.gov/pubmed/24052939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.04.003
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge