WNT3A Promotes Hematopoietic or Mesenchymal Differentiation from hESCs Depending on the Time of Exposure

We investigated the role of canonical WNT signaling in mesoderm and hematopoietic development from human embryonic stem cells (hESCs) using a recombinant human protein-based differentiation medium (APEL). In contrast to prior studies using less defined culture conditions, we found that WNT3A alone w...

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書誌詳細
主要な著者: Gertow, Karin, Hirst, Claire E., Yu, Qing C., Ng, Elizabeth S., Pereira, Lloyd A., Davis, Richard P., Stanley, Edouard G., Elefanty, Andrew G.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2013
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757745/
https://ncbi.nlm.nih.gov/pubmed/24052942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.04.002
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