WNT3A Promotes Hematopoietic or Mesenchymal Differentiation from hESCs Depending on the Time of Exposure

We investigated the role of canonical WNT signaling in mesoderm and hematopoietic development from human embryonic stem cells (hESCs) using a recombinant human protein-based differentiation medium (APEL). In contrast to prior studies using less defined culture conditions, we found that WNT3A alone w...

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Autors principals: Gertow, Karin, Hirst, Claire E., Yu, Qing C., Ng, Elizabeth S., Pereira, Lloyd A., Davis, Richard P., Stanley, Edouard G., Elefanty, Andrew G.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757745/
https://ncbi.nlm.nih.gov/pubmed/24052942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.04.002
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