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Lipofuscin: formation, effects and role of macroautophagy()

Oxidative stress plays a crucial role in the development of the aging process and age dependent diseases. Both are closely connected to disturbances of proteostasis by protein oxidation and an impairment of the proteasomal system. The final consequence is the accumulation of highly cross-linked unde...

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Detalhes bibliográficos
Main Authors: Höhn, Annika, Grune, Tilman
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757681/
https://ncbi.nlm.nih.gov/pubmed/24024146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.01.006
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