Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes()

Manganese superoxide dismutase, encoded by the Sod2 gene, is a ubiquitously expressed mitochondrial antioxidant enzyme that is essential for mammalian life. Mice born with constitutive genetic knockout of Sod2 do not survive the neonatal stage, which renders the longitudinal study of the biochemical...

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Detalhes bibliográficos
Main Authors: Cyr, Anthony R., Brown, Kyle E., McCormick, Michael L., Coleman, Mitchell C., Case, Adam J., Watts, George S., Futscher, Bernard W., Spitz, Douglas R., Domann, Frederick E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757676/
https://ncbi.nlm.nih.gov/pubmed/24024150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.01.001
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