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Sulfur amino acids regulate translational capacity and metabolic homeostasis through modulation of tRNA thiolation

Protein translation is an energetically demanding process that must be regulated in response to changes in nutrient availability. Herein, we report that the thiolation status of wobble-uridine (U(34)) nucleotides present on lysine, glutamine or glutamate tRNAs reflects intracellular methionine and c...

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Bibliografski detalji
Glavni autori: Laxman, Sunil, Sutter, Benjamin M., Wu, Xi, Kumar, Sujai, Guo, Xiaofeng, Trudgian, David C., Mirzaei, Hamid, Tu, Benjamin P.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757545/
https://ncbi.nlm.nih.gov/pubmed/23870129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.06.043
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