β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Na(v)1.7 in HEK293 cells

Voltage-gated sodium channels (Na(v)s) are glycoproteins composed of a pore-forming α-subunit and associated β-subunits that regulate Na(v) α-subunit plasma membrane density and biophysical properties. Glycosylation of the Na(v) α-subunit also directly affects Na(v)s gating. β-subunits and glycosyla...

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Autori principali: Laedermann, Cédric J., Syam, Ninda, Pertin, Marie, Decosterd, Isabelle, Abriel, Hugues
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757325/
https://ncbi.nlm.nih.gov/pubmed/24009557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00137
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