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Acetylation of the Cell-Fate Factor Dachshund Determines p53 Binding and Signaling Modules in Breast Cancer

Breast cancer is a leading form of cancer in the world. The Drosophila Dac gene was cloned as an inhibitor of the hyperactive epidermal growth factor (EGFR), ellipse. Herein, endogenous DACH1 co-localized with p53 in a nuclear, extranucleolar compartment and bound to p53 in human breast cancer cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Ke, Wu, Kongming, Gormley, Michael, Ertel, Adam, Wang, Jing, Zhang, Wei, Zhou, Jie, DiSante, Gabriele, Li, Zhiping, Rui, Hallgeir, Quong, Andrew A., McMahon, Steven B., Deng, Haiteng, Lisanti, Michael P., Wang, Chenguang, Pestell, Richard G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757249/
https://ncbi.nlm.nih.gov/pubmed/23798621
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