The Endogenous Cell-Fate Factor Dachshund restrains Prostate Epithelial Cell Migration via Repression of Cytokine Secretion via a CXCL Signaling Module

Prostate cancer (PCa) is the second leading form of cancer death in men. In a subset of PCa patients increased chemokine signaling IL-8 and IL-6 correlates with androgen therapy-resistant prostate cancer (CRPC). IL-8 and IL-6 are produced by prostate epithelial cells and promote PCa cell invasion, h...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Chen, Ke, Wu, Kongming, Jiao, Xuanmao, Wang, Liping, Ju, Xiaoming, Wang, Min, Di Sante, Gabriele, Xu, Shaohua, Wang, Qiong, Li, Kevin, Sun, Xin, Xu, Congwen, Li, Zhiping, Casimiro, Mathew C., Ertel, Adam, Addya, Sankar, McCue, Peter, Lisanti, Michael P., Wang, Chenguang, Davis, Richard J., Mardon, Graeme, Pestell, Richard G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433595/
https://ncbi.nlm.nih.gov/pubmed/25769723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0611
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