Structural Insights into the Neutralization Mechanism of Monoclonal Antibody 6C2 against Ricin

Ricin belongs to the type II ribosome-inactivating proteins that depurinate the universally conserved α-sarcin loop of rRNA. The RNA N-glycosidase activity of ricin also largely depends on the ribosomal proteins that play an important role during the process of rRNA depurination. Therefore, the stud...

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Détails bibliographiques
Auteurs principaux: Zhu, Yuwei, Dai, Jianxin, Zhang, Tiancheng, Li, Xu, Fang, Pengfei, Wang, Huajing, Jiang, Yongliang, Yu, Xiaojie, Xia, Tian, Niu, Liwen, Guo, Yajun, Teng, Maikun
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Protein Structure and Folding
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757180/
https://ncbi.nlm.nih.gov/pubmed/23853097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.480830
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